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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000733378 2 5 -DIMETHOXY-1 1 500MG
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Medchemexpress LLC 3-(3,4-dihydroxyphenyl)-7-hydroxychromen-4-one | 485-63-2 | MFCD00143002 | 99.8% | 270.24 g/mol | C15H10O5 | 10MM 1ML
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7,3',4'-Trihydroxyisoflavone is an isoflavone research compound provided as a ready-to-use 10 mM solution in DMSO for biochemical and cell-based studies. It functions as a Cot/MKK4 inhibitor and is used to investigate signaling pathways, enzyme inhibition, and isoflavone metabolism.
- Ready-to-use 10 mM solution in DMSO, one mL vial.
- High purity: 99.8% (reported).
- Chemical formula C15H10O5 and molecular weight 270.24 g/mol.
- CAS number 485-63-2 for unambiguous identification.
- Storage recommendations: powder at -20°C; solution at -80°C for long-term stability.
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Medchemexpress LLC Ruboxistaurin mesylate | 192050-59-2 | MFCD09970504 | 99.9% | 564.65 | C29H32N4O6S | 25 MG
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Ruboxistaurin mesylate is the methanesulfonate salt of ruboxistaurin, a potent, orally active, ATP-competitive inhibitor of protein kinase C beta (PKCβ). It exhibits low-nanomolar potency against PKCβ isoforms and is supplied as a high-purity solid for in vitro and preclinical research into PKCβ-related signaling, diabetic complications, and cardiovascular or ocular disease models.
- Selective PKCβ inhibition (IC50 ≈ 4.7-5.9 nM).
- High purity suitable for research use.
- Mesylate salt form with DMSO solubility for assay preparation.
- Supplied as a characterized solid with batch documentation.
- Appropriate for in vitro and preclinical pathway and disease-model studies.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000739017 TAMRA AMINE 5-ISOME 5MG
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Medchemexpress LLC 7-Bromoquinoline | 4965-36-0 | 208.06 | 25 G
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7-Bromoquinoline is a biochemical reagent that serves as an organic compound for various life science research applications. It has a high purity of 99.95%.
- Used as a biological material
- Used as an organic compound for life science related research
- Molecular formula: C9H6BrN
- Appears as a solid below 32°C and liquid above 36°C
- Light yellow to yellow color
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430661 Q AGAROSE HP 25ML
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Cambridge Isotope Laboratories 1 2 4 5 8-PentaCN (PCN-59) (unlabeled) 100 ug/mL in nonane 1 mL
1 2 4 5 8-PentaCN (PCN-59) (unlabeled) 100 ug/mL in nonane 1 mL
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431019 CYANINE3 AMINE TFA 1MG
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![Apexbio Technology LLC parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] 25mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096693.png-250.jpg)
Apexbio Technology LLC parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] 25mg
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Parathyroid hormone (7-34) is a polypeptide antagonist targeting parathyroid hormone receptors (PTH1R and PTH2R) It is derived from Homo sapiens and Macaca fascicularis and is designed to modulate PTH receptor activity thereby influencing calcium and phosphate homeostasis Parathyroid hormone (7-34) exerts its biological activity primarily through competitive interaction with PTH receptors affecting absorption processes in bone kidney and intestinal tissues Based on these pharmacological properties parathyroid hormone (7-34) holds research potential in studies of mineral metabolism bone remodeling and calcium-phosphate balance disorders
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Apexbio Technology LLC LDK378 1032900-25-6 200mg
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LDK378 (CAS 1032900-25-6) is a potent inhibitor of anaplastic lymphoma kinase (ALK) a receptor tyrosine kinase within the insulin receptor superfamily It exhibits an in vitro IC50 of 200 pM for ALK and displays moderate to high inhibitory activity against a limited set of other kinases including IGF-1R (IC50 8 nM) InsR (IC50 7 nM) and STK22D (IC50 23 nM) LDK378 suppresses proliferation of Ba/F3 cells transfected with NPM-ALK fusion and Karpas 299 human lymphoma cells harboring NPM-ALK with IC50 values of 22 8 nM and 26 nM respectively The compound is widely used in preclinical studies to investigate ALK-driven signaling and its potential as a therapeutic target in oncology
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Apexbio Technology LLC ASP3026 1097917-15-1 200mg
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ASP3026 (CAS 1097917-15-1) is a selective inhibitor of anaplastic lymphoma kinase (ALK) exhibiting an IC50 of 3 5 nM for ALK enzymatic inhibition When evaluated across a panel of 86 tyrosine kinases ASP3026 demonstrated highest selectivity for ALK ROS and ACK kinases In cellular studies ASP3026 inhibited the proliferation of EML4-ALK-expressing NCI-H2228 non-small cell lung cancer (NSCLC) cells (IC50 64 8 nM) and reduced viability in NPM-ALK anaplastic large cell lymphoma (ALCL) lines with IC50 values ranging from 0 4 to 2 5 M In vivo oral administration of ASP3026 in mouse xenograft models suppressed ALK phosphorylation and significantly reduced tumor growth ASP3026 serves as a valuable tool for investigating ALK-driven oncogenesis and for preclinical evaluation of ALK-targeted therapies
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Medchemexpress LLC Mivavotinib monohydrochloride | 1952251-28-3 | 99.9% | 380.85 g/mol | C17H22ClFN6O | 5 MG
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Mivavotinib monohydrochloride is an investigational small-molecule dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), supplied as a white to off-white solid for research use. The monohydrochloride salt displays low-nanomolar inhibitory activity against SYK and FLT3 and is provided with high purity for preclinical studies.
- Dual SYK/FLT3 inhibitor for preclinical research.
- High purity (99.9%).
- White to off-white solid formulation.
- Provided as a monohydrochloride salt for improved stability.
- Low-nanomolar potency against target kinases.
- Store at 4°C and protect from moisture for long-term stability.
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Ambeed AMBEED
5000868263 6-BROMOQUINOLINE-2-CARBOXY 1GR
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![Medchemexpress LLC Ethanesulfonic acid, 2-[(aminoiminomethyl)amino]- | 543-18-0 | 99.9% | 167.19 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000436072-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Ethanesulfonic acid, 2-[(aminoiminomethyl)amino]- | 543-18-0 | 99.9% | 167.19 | 100 MG
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Guanidinoethyl sulfonate (Standard) is an analytical standard and an orally available, blood-brain permeable competitive inhibitor of taurine transporters. It acts as a competitive antagonist of glycine receptors (GlyR) (IC50=565 μM) and shows weak agonist/antagonist effects on GABAA receptors. It inhibits taurine transmembrane transport, blocks glycine-mediated chloride influx, and may regulate brain pH for neuroprotective effects, useful in studies of ischemic brain injury. It is applied in qualitative, quantitative, and methodological research experiments including HPLC, GC, and MS.
- Analytical standard for research
- Orally available and blood-brain permeable
- Inhibits taurine transporters
- Antagonizes glycine receptors
- Modulates GABAA receptors
- Blocks glycine-mediated chloride influx
- May offer neuroprotective effects
- Used in HPLC, GC, and MS applications
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eMolecules 5622-36-6 | Methyl 2-(quinolin-6-yl)acetate | Synthonix - Stock | MFCD04038669 | 201.225 | C12H11NO2 | 95.000 | COC(=O)Cc1ccc2ncccc2c1 | 1g | 476497818
Methyl 2-(quinolin-6-yl)acetate | Synthonix - Stock | 5622-36-6 | MFCD04038669 | 201.225 | C12H11NO2 | 95.000 | COC(=O)Cc1ccc2ncccc2c1 | 1g | 476497818
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